The Feldbrügge lab is using in vivo approaches to study mRNA transport and local translation. We focus on the tight coupling between mRNA and membrane trafficking using endosomal long-distance transport along microtubules as an example.
Within the FOR2333 Research Unit we study:
In close collaboration with the König and Zarnack lab, we investigate how the key RNA-binding protein Rrm4 coordinates translation and transport of cargo mRNAs. To this end we focus on the precise binding behaviour of Rrm4 at landmark sites of translation mediated by the concerted action of its three RRM domains.
Michael Feldbrügge is Co-Speaker of the FOR2333 Research Unit.
Prof. Dr. Michael Feldbrügge
Heinrich-Heine University Düsseldorf
Center for Excellence on Plant Sciences and Bioeconomy Science Center, Feldbrügge lab, Institute for Microbiology, Dep. Biology
Website at University Düsseldorf
Prof. Dr. Dierk Niessing (Sprecher)
Ulm University - Institute of Pharmaceutical Biotechnology
James Franck Ring N27
Phone: +49 89 3187 2176